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ACT-132577 Size:Solid 10 mg InChi: InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26

SKU: 22798519880

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Description

InChi: InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26

) also results in reductions in colony counts in tissues compared with those in the tissues of Guinea pigs treated with caspofungin acetate (the difference is not statistically significant) and improves the survival times but does not sterilize tissues

InChiKey: MIIIKWNQFDQJGS-GIJPFRRLSA-N

ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2

ACT-132577 Size:Solid 10 mg InChi: InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26Aprocitentan, also known as ACT 132577, is an endothelin receptor antagonist and an pharmacologically active metabolite of macitentan. Aprocitentan antagonized the specific binding of ET 1 on membranes of cells overexpressing ET(A) and ET(B) receptors and blunted ET 1 induced calcium mobilization in various natural cell lines, with inhibitory constants within the nanomolar range. Product information CAS Number: 1103522 45 7 Molecular Weight: 546. 19

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