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The total amount of NS3 in the ACH-806-treated sample is reduced by ~6-fold (100/16) and causes a reduction of NS4A-bound NS3 ~29-fold (261/9)
PROTAC has been developed having structure A-L-B that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compond via a suitable linker
Sofosbuvir metabolite GS-331007 13CD3
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock
TC-E 5001 9913 The total amount of NS3Product information CAS Number: 865565 29 3 Molecular Weight: 409. 46 Formula: C20H19N5O3S Chemical Name: 3 (4 methoxyphenyl) 5 ({[4 (4 methoxyphenyl) 5 methyl 4H 1,2,4 triazol 3 yl]sulfanyl}methyl) 1,2,4 oxadiazole Smiles: CC1=NN=C(SCC2=NC(=NO2)C2C=CC(=CC=2)OC)N1C1C=CC(=CC=1)OC InChiKey: LQZSHPITKSPDLC UHFFFAOYSA N InChi: InChI=1S C20H19N5O3S c1 13 22 23 20(25(13)15 6 10 17(27 3)11 7 15)29 12 18 21 19(24 28 18)14 4 8 16(26 2)9 5 14 h4 11H,12H2,1 3H3
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