Piclamilast 578MI977 2CH4O3S/c39-31(37-27-5-1-3-25(19-27)29-33-15-16-34-29)23-11-7-21(8-12-23)22-9-13-24(14-10-22)32(40)38-28-6-2-4-26(20-28)30-35-17-18-36-30

2CH4O3S/c39-31(37-27-5-1-3-25(19-27)29-33-15-16-34-29)23-11-7-21(8-12-23)22-9-13-24(14-10-22)32(40)38-28-6-2-4-26(20-28)30-35-17-18-36-30

InChiKey: HEKJYZZSCQBJGB-UNOMPAQXSA-N

CAS Number: 77-59-8

TNF and IL-6 in clinical trials for patients with rheumatoid arthritis

Piclamilast 578MI977 2CH4O3S/c39-31(37-27-5-1-3-25(19-27)29-33-15-16-34-29)23-11-7-21(8-12-23)22-9-13-24(14-10-22)32(40)38-28-6-2-4-26(20-28)30-35-17-18-36-30Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively. Product information CAS Number: 144035 83 6 Molecular Weight: 381. 25 Formula: C18H18Cl2N2O3 Chemical Name: 3 (cyclopentyloxy) N (3,5 dichloropyridin 4 yl) 4 methoxybenzamide Smiles: COC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl InChiKey: RRRUXBQSQLKHEL UHFFFAOYSA N InChi: InChI=1S C18H18Cl2N2O3 c1 24