AG-494 - CAS# 133550-35-3 lin hydrochloride and c-Kit and has no

and c-Kit and has no inhibitory to Ins-R

386(3):197-204

Suplatast tosilate also significantly inhibits the secretion of CCL17

CAS Number: 1135237-88-5

AG-494 - CAS# 133550-35-3 lin hydrochloride and c-Kit and has noAG 494 (Tyrphostin AG 494) is a potent and selective EGFR tyrosine kinase inhibitor (IC50=0. 7 M). AG 494 inhibits the autophosphorylation of EGFR, ErbB2, HER1 2 and PDGF R with IC50s 1. 1, 39, 45 and 6 M, respectively. AG 494 blocks Cdk2 activation and inhibits EGF dependent DNA synthesis. Product information CAS Number: 133550 35 3 Molecular Weight: 280. 28 Formula: C16H12N2O3 Synonym: Tyrphostin AG 494 Chemical Name: (2E) 2 cyano 3 (3, 4